Whole-tumor radiomics analysis of DKI and DTI may improve the prediction of genotypes for astrocytomas: A preliminary study

Y Tan, W Mu, X Wang, G Yang, RJ Gillies… - European journal of …, 2020 - Elsevier
Purpose To test whether the whole-tumor radiomics analysis of DKI and DTI images could
predict IDH and MGMTmet genotypes of astrocytomas. Method Sixty-two astrocytomas were
enrolled. 364 radiomics features of whole tumor were extracted from mean-kurtosis (MK),
and mean-diffusivity (MD) images, respectively. The multivariable logistic regression was
used to select the most meaningful radiomics features for predicting IDH and MGMTmet
genotypes. A radiomics model was built by logistic linear regression. A combined model was …
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